Mosquito-borne tropical diseases have significantly impacted human life worldwide, as evidenced by arboviruses such as Dengue and Yellow Fever, Chikungunya, Zika, and Encephalitis Virus Fever, among others. Additionally, parasitic diseases, including malaria, leishmaniasis, and filariasis, have also had a profound effect. To address various aspects of research on these mosquito-borne diseases, several authors contributed to the construction of this book. Evolutive strategies related to the emergence of hematophagous insects and general aspects involving the transmission of pathogens, as well as common elements of their pathophysiology, are discussed. The immunopathologic characteristics of Dengue Fever, which hinder the development of a safe and efficient vaccine, are discussed in different chapters addressing Dengue Fever epidemiology, physiopathology, and control strategies, including the available vaccines. Epidemiology, control strategies and biological characteristics of mosquito-borne parasitic diseases are also discussed in the book, including malaria, leishmaniasis and filariasis. The issue of climate change and its impact on tropical diseases transmitted by mosquitoes is also addressed in this book, which provides up-to-date information for anyone interested in this topic, which is essential for human health.